This comprehensive compendium unravels the intricacies of three common and daunting skeletal disorders: osteoporosis, osteoarthritis, and rheumatoid arthritis. These ailments afflict people across all age groups, demanding a deeper understanding of their diagnostic, prognostic, preventive, and therapeutic dimensions. It presents seven key topics written by medical experts that explore research on these diseases: Chronic Lung Disease and Osteoporosis An exploration of the intricate link between chronic lung ailments and osteoporosis. AI Detection of Knee Osteoarthritis Recent use of artificial intelligence aiding knee osteoarthritis identification. Inflammatory Signalling in Rheumatoid Arthritis Covers the role of cytokines and chemokines in the context of rheumatoid arthritis. Vitamin D, Immune System, and Bone Health Unveils the vital implications of Vitamin D on the immune system and bone health. Bone Water and Hydration Effects A review of the impact of drugs on bone hydration status through the lens of bone water. Dietary Patterns and Rheumatoid Arthritis An analysis of the connection between dietary habits and rheumatoid arthritis. Quality of Life in Rheumatoid Arthritis Patients (Chapters 112-130): An examination of the self-perceived quality of life in Rheumatoid Arthritis patients, comparing South Asian and British White populations. This knowledge-rich treatise is a valuable resource for patients and their families battling these skeletal ailments. It's equally beneficial for medical students, orthopedists, researchers, and anyone eager to grasp the complexities of these widespread skeletal pathologies.

Learn the skills of medical history taking and physical examination with this accessible and comprehensive textbook. Designed for medical students and clinicians, it simplifies complex concepts and procedures to empower you with essential skills for effective patient consultation. Key Features -Clear and Simple Language: This book uses plain and straightforward language, making the intricate world of medical history taking and physical examination easy to understand, even for beginners. -Real Illustrations: Learn from real pictures that vividly depict clinical scenarios, helping you bridge the gap between theory and practice. -Step-by-Step Guidelines: Follow systematic guidelines for history taking and physical examination. From patient introduction and consent to comprehensive body system examinations, each step is clearly outlined, ensuring you never miss a crucial detail. -Specialized Examination Section: Includes a specialized examination section, covering various body systems like cardiovascular, respiratory, abdominal, and the central nervous system. Understand the physical basis of clinical signs to enhance your diagnostic skills. Quick Guide in History Taking and Physical Examination helps you to master the art of clinical examination, develop the confidence to take accurate medical histories, and interpret symptoms and signs effectively. It serves as an essential companion for medical students and residents on their journey to become a proficient clinician.

Globalization and economic progress has been accompanied with an increase in the incidence of obesity, cardiovascular disease and other non-communicable illnesses worldwide among populations in some countries. Obesity and Disease examines how these rising epidemics of obesity and other lifestyle problems are changing health guidelines globally - from directing health care professionals on how to care for individuals to encouraging them to embrace the interconnected systems involved in chronic disease risk management, prevention and treatment. With a focus on systems, this reference serves as an excellent resource on how to develop a more comprehensive approach to population health. Starting with a systematic approach to health risk assessment in section one, followed by a targeted approach to risk reduction and prevention in section two, the eBook moves along seamlessly into section three calling for a shared responsibility toward strengthening health systems globally that can help determine and improve upon the health of individuals, and societies across the world. Obesity and Disease gives applicable concepts to readers in a multidisciplinary and collaborative approach to alter health systems and implement changes that promote health and wellness in the communities they serve and live in. The information and resources in this eBook also serve as a guideline for collaborations across professional associations with a goal of developing strategic plans to combat obesity and diabetes.

Pharmacological and Molecular Perspectives on Diabetes is a compilation of reviews on clinical and scientific aspects of diabetes mellitus. It presents 11 contributions by eminent scholars that give the reader rational pharmacological and genetic perspectives of the disease and its treatment. The reviews approach diabetes from different angles, and highlight research that has been done to understand some questions about the molecular biology of diabetes in experimental settings. Topics of clinical significance such as the use of different hypoglycemic agents, and diabetic complications in clinical settings are also covered. Topics included in this book are: - Epigenetic alterations and type 2 diabetes mellitus - Responses to nutritional chromium supplements for type 2 diabetes mellitus - Endocrine role of osteocalcin in homeostatic regulation of glucose metabolism - Effect of diabetes on memory - Osteoarthritis in relation to type 2 diabetes mellitus: prevalence, etiology, symptoms and molecular mechanism - Infection of novel coronavirus in patients with diabetes mellitus - Role of an anti-inflammatory agent in the management of type 2 diabetes mellitus - Role of antidiabetic agents which helps regulates TCF7L2 variations in type 2 diabetes mellitus - Relationship between type 2 diabetes mellitus, PCOD and neurological disorders: role of antidiabetic drugs Comparison of different types of insulin available for type 1 diabetes treatment - Circadian rhythm disruption: special reference to type 2 diabetes mellitus - Type 2 diabetes mellitus and its complications: pharmacogenetics based correlations and circulating microRNA as biomarkers Pharmacological and Molecular Perspectives on Diabetes should prove to be of interest to all pharmaceutical and molecular biology scientists who are involved in research in anti-diabetic drug design and discovery, and practicing endocrinologists who wish to keep abreast of recent developments in the field.

Type 2 diabetes (T2D) is a complex metabolic disorder characterized by impaired glucose metabolism and pancreatic β-cell dysfunction. No effective treatments are available for T2D, although there have been many developments in the therapeutic arena. Nitric oxide (NO) is an endocrine agent with multiple and important biological roles in most mammalian tissues. NO has emerged as a central regulator of energy metabolism and body composition. NO bioavailability is decreased in T2D. Several of the pharmaceuticals used in T2D affect the NO system and perhaps even more so by the drugs we use to treat diabetic cardiovascular complications. Experimental works in animal models of T2D show promising results with interventions aimed to increase NO signaling. However, translation into human studies has so far been less successful, but more large-scale prolonged studies are clearly needed to understand its role. This book is a collection of reviews that deal with the role of nitric oxide in type 2 diabetes, providing a unique overview of NO signaling, and pointing out key areas for more detailed research. The book includes contributions about the pathophysiology of T2D, a brief history of discovery and timeline of NO research, a comprehensive overview of impaired NO metabolism in T2D, precursors of NO (i.e., L-arginine, L-citrulline, nitrate, nitrites, and NO donors), NO and T2D from genetic points of view, NO and diabetic wound healing, NO and osteoporosis, NO and hyperuricemia, NO and Alzheimer's Disease, therapeutic applications of NO and NO donors in T2D. The compilation is of great value to anyone interested in the biochemistry of NO and its relationship to diabetes.