Rare-earth hexaborides are a group of materials composed of octahedral boron units. They are useful for making advanced ceramics that have a wide range of industrial applications due to their low electronic work functions, hardness, refractory properties, low electrical resistances and specific thermal expansion coefficients. Rare-Earth Metal Hexaborides: Synthesis, Properties, and Applications provides a quick reference on rare-earth metal hexaborides and their engineering applications. It provides a primer on rare earth elements followed by details of rare-earth hexaboride structures, synthetic methods, and information about their alloys and ceramic composites. References to scholarly research are also provided for assisting advanced readers. This reference is a handy source of information for chemical engineering and materials science scholars, and anyone interested in the applied chemistry of rare-earth metals and borides.

Medicinal chemists around the world have been inspired by nature and have successfully extracted chemicals from plants. Research on enzymatic modifications of naturally occurring compounds has played a critical role in the search for biologically active molecules to treat diseases. This book set explores compounds of interest to researchers and clinicians. It presents a comprehensive analysis about the medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, molecular modelling studies) of different compounds. Each chapter brings contributions from known scientists explaining experimental results which can be translated into clinical practice. Volume 2 gives (1) a detailed overview of the sesquiterpenes polypharmacology, (2) an interesting journey around the world of cannabinoids that reveals the development of new synthetic Δ9-THC derivatives, (3) the design of specific formulations to overcome the volatility of small sized terpenes-based essential oils, (4) an update on the latest generations of endoperoxides endowed with antimalarial activity and finally (5) a summary of MedChem strategies to fix the most common issues in formulating terpene derivatives (like low potency and poor solubility). The objective of this book set is to fulfill gaps in currently acquired knowledge with information from the recent years. It serves as a guide for academic and professional researchers and clinicians.

Advanced Catalysts Based on Metal-organic Frameworks is a comprehensive introduction to advanced catalysts based on MOFs. It covers basic information about MOF catalysts with industrial and environmental applications. The detailed chapters update readers on current applications and strategies to apply MOF-based catalysts in industrial processes geared for sustainability initiatives such as renewable energy, pollution control and combating carbon emissions. Key Features - 13 structured, easy to read chapters that comprehensively cover MOF catalysts - An introduction to basic information about MOF catalysts - In-depth coverage of advanced applications of MOF catalysts - Explanation of MOF modifications and applications of derivative compounds - In-depth coverage of MOF catalysts used for electrocatalysis and photocatalysis - Detailed explanation of environmental-friendly and sustainable technologies (biomass upgrading, water purification, CO2 capture) - Updated references for advanced readers The is an essential reference for chemical engineers, scientists in the manufacturing and sustainability industry and post-graduate scholars working on MOFs and chemical catalysis.

The book is an evidence-based reference about biochemical mechanisms of action of plant secondary metabolites. It conveys an understanding about how plant-based therapies work, and explains their role in the treatment of complementary and alternative medicine for in the treatment of diabetes, cancer, neurodegenerative disorders, microbial infections, etc., The 15 chapters are written by eminent scholars, lecturers, and experts in indigenous knowledge systems (IKS), industrial and medicinal plants, phytotherapeutics, and phytoinformatics. Reports on health benefits of specific phytochemicals are also highlighted. In addition to basic concepts in medicinal chemistry and ethnopharmacology, the book covers the role of modern computer techniques in developing new pharmaceuticals from plat sources. Therapeutic Uses of Plant Secondary Metabolites is timely and valuable reference for both undergraduate and postgraduate students in medicinal chemistry, as well as researchers and professionals in IKS, phytomedicine, ethnopharmacology, phytopharmacology, plant biotechnology, drug discovery and development, and phytotherapeutics.

Frontiers in Computational Chemistry presents contemporary research on molecular modeling techniques used in drug discovery and the drug development process: computer aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. The sixth volume of this series features these six different perspectives on the application of computational chemistry in rational drug design: - Computer-aided molecular design in computational chemistry - The role of ensemble conformational sampling using molecular docking and dynamics in drug discovery - Molecular dynamics applied to discover antiviral agents - Pharmacophore modeling approach in drug discovery against the tropical infectious disease malaria - Advances in computational network pharmacology for Traditional Chinese Medicine (TCM) research - Progress in electronic-structure based computational methods: from small molecules to large molecular systems of biological significance

This volume is a comprehensive compilation of contributions on the state of art knowledge about bioactive compounds including their sources, isolation methods, biological effects, health benefits and potential applications. These bioactive compounds could serve as alternatives in the prevention or treatment of multifactorial diseases for vulnerable population groups. Chapters in the book incorporate the knowledge based on traditional medicine with recent findings on bioactive molecules and their pharmaceutical implications in neurodegenerative diseases, cancer, COVID 19, diabetes, immunomodulation and farm animal diseases. The book also highlights the latest breakthroughs in the field of screening, characterization, and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, algae, fungi, higher plants, and marine sources. Authors from renowned institutions of India, Japan and China have shared their expertise in the contributed chapters with the goal of enhancing readers’ knowledge about the significance of use of bioactives in therapeutics and nutraceuticals. It is an informative reference for researchers, professors, graduate students, science enthusiasts, and all those who wish to gain insights into various aspects of bioactive compounds and development of new pharmacological active constituents and nutritional science.

This reference describes the chemistry of organocalcium compounds that contain a Ca-C σ-bond. It collects the information about this niche group of organometallic compounds into 4 easy-to-read chapters. It is intended for scholars in the field of organic chemistry, and researchers in industrial chemistry and chemical engineering departments. Key features: - Presents a comparison to homologous compounds of other alkaline earth metals. - Explains the main problems encountered in the synthesis of organocalcium compounds with reference to the reactivity of calcium, the low solubility in common solvents and the high reactivity of the formed intermediates and products - Highlights many concepts about the Ca-C bond such as the steric hindrance, degrading agent properties, organocalcium spectroscopy, and more

This reference provides collective information about the physical and photophysical changes of supramolecules after encapsulation. It covers luminescent systems involving a range of host molecules such as calixarenes, cyclodextrin, resorcinanene-crowns, pillararenes, cucurbituril, and metallacycles. Chapters also discuss the effect of the macrocyclic environment on the properties of functionalized molecules, including the variations in folding and unfolding patterns. Each chapter is supplemented with detailed references, making this an ideal resource for scholars interested in supramolecular photophysics.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. Contents of this volume include these 6 reviews: - Multicomponent synthesis of heterocycles by microwave irradiation - Stereoselective procedures for the synthesis of olefines - Advanced microwave assisted organic synthesis method in organic chemistry - Five and six-membered n-heterocycle rings from diaminomaleonitrile - Peptidomimetics: current and future perspectives on hiv protease inhibitors - A review on synthesis, chemistry, and medicinal properties of benzothiazines and their related scaffolds

Frontiers in Natural Product Chemistry is a book series devoted to important advances in natural product chemistry. The series features volumes that cover all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. Volume 10 of the series brings together 5 reviews on a variety of bioactive compounds. · An overview of cistus species growing in Sardinia: a source of bioactive compounds · Roles of natural abscisic acids in fruits during fruit development and under environmental stress · Progress in the research of naturally occurring biflavonoids: a look through · Plant metabolites for protecting human cells against radiation-associated damage: an integrative review · Chemical perspective and drawbacks in flavonoid estimation assays